Increased detection of pharyngeal and rectal gonorrhea in men who have sex with men after transition from culture to nucleic acid amplification testing

VJ Cornelisse; EPF Chow; S Huffam; CK Fairley; M Bissessor; V De Petra; BP Howden; I Denham; CS Bradshaw; D Williamson; MY Chen

Journal article

Increased detection of pharyngeal and rectal gonorrhea in men who have sex with men after transition from culture to nucleic acid amplification testing

VJ Cornelisse, EPF Chow, S Huffam, CK Fairley, M Bissessor, V De Petra, BP Howden, I Denham, CS Bradshaw, D Williamson, MY Chen

Sexually Transmitted Diseases | LIPPINCOTT WILLIAMS & WILKINS | Published : 2017

DOI: 10.1097/OLQ.0000000000000553

Abstract

Background: This before-and-after study measured the impact of a change in testingmethods from culture to nucleic acid amplification testing (NAAT) on the detection of pharyngeal and rectal gonorrhea in men who have sex with men (MSM) on a sexual health service level, including the effect on subgroups anticipated to have higher rates of gonorrhea. Methods: In March 2015, Melbourne Sexual Health Centre changed its laboratory method for gonococcal testing from culture to NAAT using the Aptima Combo 2 and Aptima GC tests. We compared the proportion of tests positive for rectal and pharyngeal gonorrhea in MSM using culture in 2014 with those using NAAT in 2015. Results: The proportion of tests p..

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University of Melbourne Researchers

Eric Chow Author

Ben Howden Author

Catriona Bradshaw Author

Deborah Williamson Author

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Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by Australian NHMRC

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This research was supported by the Australian National Health and Medical Research Council (NHMRC) program grant (number 568971). E.P.F.C. is supported by the Early Career Fellowships from the Australian NHMRC (number 1091226).